Publications
Independent Career
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Publications and Patents from Ph.D. and Postdoctoral Studies
- Jones, K., A.; Kentala, K.; Beck, M. W.; An, W.; Lippert, A. R.; Lewis, J. C.; Dickinson, B. C. ACS Cent. Sci. 2019, 5, 1768. "Development of a Split Esterase for Protein–Protein Interaction-Dependent Small-Molecule Activation"
- Featured in ACS Cent. Sci. 2019, 5, 1744.
- Preprint version available at ChemRxiv
- Dickinson, B.C.; Kathayat, R.S.; Beck, M.W. “Synthetic Substrates for Enzymes That Catalyze Reactions of Modified Cysteines and Related Methods.” U.S. Patent 10,413,583, September 17, 2019.
- Qiu, T.*; Kathayat, R. S.*; Cao, Y.*; Beck, M. W.; Dickinson, B. C. Biochemistry 2018, 57, 221. "A Fluorescent Probe with Improved Water Solubility Permits the Analysis of Protein S-Depalmitoylation Activity in Live Cells"
- Beck, M. W.; Derrick, J.S.; Suh, J.-M.; Kim, M.; Korshavn, K. J.; Kerr, R. A.; Cho, W. J.; Larsen, S. D.; Ruotolo, B. T.; Ramamoorthy, A.; Lim, M. H. ChemMedChem 2017, 12, 1828. "Minor Structural Variations of Small Molecules Tune Regulatory Activities Toward Pathological Factors in Alzheimer's Disease"
- Featured on Front Cover
- Beck, M. W.; Kathayat, R. S; Cham, C. M.; Chang, E. B.; Dickinson, B. C. Chem. Sci. 2017, 8, 7588. “Michael Addition-Based Probes for Ratiometric Fluorescence Imaging of Protein S-Depalmitoylases in Live Cells and Tissues”
- Beck, M. W.*; Derrick, J. S.*; Kerr, R. A.; Oh, S. B.; Cho, W. J.; Lee, S. J. C.; Ji, Y.; Han, J.#; Tehrani, Z. A.; Suh, N.; Kim, S.; Larsen, S. D.; Kim, K. S.; Lee, J.-Y.; Ruotolo, B. T.; Lim, M. H. Nature Commun. 2016, 7, 13115. "Structure-Mechanism-Based Engineering of Chemical Regulators Targeting Distinct Pathological Factors in Alzheimer’s Disease"
- Beck, M. W.*; Oh, S. B.*; Kerr, R. A.; Lee, H. J.; Kim, S. H.; Kim, S.; Jang, M.; Ruotolo, B. T.; Lee, J.-Y.; Lim, M. H. Chem. Sci., 2015, 6, 1879. “A Rationally Designed Small Molecule for Identifying an In Vivo Link of Metal–Amyloid-β Complexes to the Pathogenesis of Alzheimer’s Disease”
- Recommended as "Very Good" on Faculty of 1000.
- Beck, M. W.; Pithadia, A. S.; DeToma, A. S.; Korshavn, K. J.; Lim, M. H. Chapter 10: Ligand Design to Target and Modulate Metal-Protein Interactions in Neurodegenerative Diseases. In Ligand Design in Medicinal Inorganic Chemistry John Wiley & Sons: Chichester, West Sussex, 2014, pp 256-286.
- Featured in Angew. Chem. Int. Ed., 2015, 54, 2324.
- Liu, Y.*#; Kochi, A.*; Pithadia, A. S.; Lee, S.; Nam, Y.; Beck, M. W.; He, X.; Lee, D.; Lim, M. H. Inorg. Chem., 2013, 52, 8121. “Tuning Reactivity of Diphenylpropynone Derivatives with Metal-Associated Amyloid-β Species via Structural Modifications”
- Pithadia, A. S.*; Kochi, A.*; Soper, M. T.; Beck, M. W.; Liu, Y.; Lee, S.; DeToma, A. S.; Ruotolo, B. T.; Lim, M. H. Inorg. Chem. 2012, 51, 12959. “Reactivity of Diphenylpropynone Derivatives Toward Metal-Associated Amyloid-β Species”
*Denotes Equal Contribution, #Denotes Undergraduate Author